I already placed a ticket, but I wanted to post as well. After 12.1 went live the ability to Keybind Shift+Function Key is broken, when you try to keybind Shift+ and any F key, only the Shift key binds to that slot. Shift+F2 through Shift+F6 at least, if bound prior to 12.1, will still function. Shift+F1 binds no longer function, and instead seem to unlock the camera. This function doesn't show in the Keybinds listings, so I can't unbind the combo, so everytime I hit Shift+F1, which I've been doing for many years now, my camera goes crazy.
I'd be super eternally grateful if these issues could be fixed to how they were in the next update.