Last night I was going into the craft hall in Snowbourn. As soon as I got in the door I discovered I was rooted to the floor - well, at least the ASWD keys were no longer working. None of the other keys were working either - I couldn't use chat but I also couldn't use my mapped keys to do anything or CMD-Tab out of LOTRO. The mouse worked - I was able to click on the door and it opened. And I could bring up the panel to allow me to logout. I tried logging out and back in, but that didn't clear up the problem. Then I tried closing the client and relaunching it. That's when I discovered I couldn't even enter my password. Then I went into Safari and tried to type in the URL field - no go. My keyboard had been completely "disconnected". I rebooted and everything was fine.
I bugged it.
EDIT: Oh, and I was in full-screen mode (had not changed the resolution or windowing in that session) and I had not changed the focus out of LOTRO and back in or anything like that either. I probably had a key depressed as I hit the door on the craft hall tho.